Scientific Research
Pioneering Innovations in Biotechnology
At Applied Biological Laboratories, our research drives the future of respiratory health. We develop first-in-class immune-modulating and anti-inflammatory solutions to strengthen natural defenses and target respiratory disease.
Building on Decades of Research
Relevant publications
Clinical efficacy of sICAM-1 our key API
https://jamanetwork.com/journals/jama/fullarticle/189972
https://pmc.ncbi.nlm.nih.gov/articles/PMC296196/
Rhinovirus in transplant recipients
https://pmc.ncbi.nlm.nih.gov/articles/PMC4303052/
https://pubmed.ncbi.nlm.nih.gov/20042728/
https://pubmed.ncbi.nlm.nih.gov/40885198/
https://pubmed.ncbi.nlm.nih.gov/35446933
https://pubmed.ncbi.nlm.nih.gov/28183847/
Rhinovirus in other vulnerable populations (elderly, immunocompromised, and chronic lung disease)
https://pubmed.ncbi.nlm.nih.gov/40155903/
https://pubmed.ncbi.nlm.nih.gov/36531535/
https://pubmed.ncbi.nlm.nih.gov/14716689/
https://pubmed.ncbi.nlm.nih.gov/28134768/
Our Approach
Translational Research for Real-World Impact on Rhinovirus and other Infections
Our multidisciplinary teams bridge fundamental science and clinical application, ensuring our discoveries translate into effective therapies.
In treating rhinovirus and other respiratory infections, we leverage proven approaches such as competitive inhibition and make them even more effective by adding them to our immune modulating platform. We believe this will greatly increase commercial feasibility and help bring these proven technologies to market.
Patented Nasal Spray: Our Technology
Our treatment is designed to strengthen the innate immune system and manage respiratory inflammation by combining proven competitive inhibitors with immune modulating proteins. These natural proteins work differently than antibodies or steroids to manage inflammatory cytokines. Cytokine pathways are interconnected and multi-faceted. Most cytokines serve multiple functions—anti-viral, reparative, and inflammatory. This is why single-target approaches to inflammation have not been entirely successful. They either increase inflammation (interferon therapy) or lower immunity (steroids) Certain natural proteins have evolved to be pleiotropic and modulate cytokine pathways to produce a strong anti-viral response without the off-target effects. Through over a decade of research, we have identified these proteins and formulated them into effective next-generation treatments for inflammation and immunity.
Industry Collaboration
We partner with organizations to accelerate biotech innovation and bring solutions to market.
Pipeline Highlights
Explore our latest breakthroughs and ongoing projects in respiratory health, immune modulation, and viral inhibition.
Why Our Research Matters
Impactful Solutions for Global Health
Our work addresses critical challenges in respiratory disease and immune health. There is currently no effective vaccine or treatment for rhinovirus even though it is the most common virus in our environment and poses serious health risks to at least 30% of the population. Our leading technology for rhinovirus can potentially save over $10B a year in hospitalization costs for the most immune compromised patients, where there are currently no treatment options. The technology can be expanded to eventually treat the broader patient population, including those with pre-existing conditions, autoimmune diseases, and the elderly.
Collaborate With Us
Interested in partnering or learning more about our research? Connect with our scientists to explore collaboration opportunities.